The effects of modafinil vary depending on who you are, but in rare cases people can experience a negative response. The reason for this is unknown as it could be due to someone’s unique makeup or personal sensitivity towards the drug itself.
Those who are starting to use modafinil for the first time can experience non-responses, but those with higher doses and/or long term usage will quickly build up a tolerance.
If you are a new user, starting with a dose of 50–100 mg, increase it to 200 mg or higher and test if the effects kick in. In doing so, keep yourself busy. Don’t wait for the active substance to kick in.
Another trick is to combine it with coffee. In fact, caffeine mixes well with smart drugs such as modafinil and can help the nootropic’s effects show faster.
If you are a long-term user, try these tricks: halt taking it for 1 week to 1 month; reduce modafinil intake to 1-3 times/week; and finally, reduce the dosage amount to 200-300mg.
It is important to note that there might be other factors contributing to the low effects of modafinil so pay close attention to your diet, medication, environment and sleep routine, to try and identify the culprit.