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Brain picture

What is modafinil?

Modafinil, sold under the brand name Provigil, is a FDA approved medication to treat sleepiness due to narcolepsy, shift work sleep disorder, and obstructive sleep apnea. It has seen off-label use as a purported cognitive enhancer to improve wakefulness.

Modafinil is also known to be a highly effective drug in treating patients with non-sleep related conditions like ADHD, multiple sclerosis, clinical depression, Parkinson’s disease, mental disorders as well as individuals with impaired cognitive function problems.

How does modafinil work?

Modafinil is a prescription medication that has been used for years to help people with excessive daytime sleepiness. The mechanism of action isn’t well-known, but scientists believe it engages different neurotransmitters associated with mental acuity and focus – including the dopamine levels in your brain.

Nonetheless, modafinil is a wake-promoting agent that functions by stimulating the brain. It’s thought to work through several varying pathways in our brains, ultimately leading up toward improving all areas of cognitive function. It has been shown time after time as an effective way for those who suffer from sleeping disorders or simply want more energy during their day.

Primarily, it increases the amount of dopamine by lowering its reuptake into the brain’s nerves. In clinical studies, modafinil shows neuroprotective and antioxidative effects in which a rise in cortical creatine or a decrease in brain oxidation promotes brain vigilance.

Active brain
Study group

Does modafinil work for everyone?

The effects of modafinil vary depending on who you are, but in rare cases people can experience a negative response. The reason for this is unknown as it could be due to someone’s unique makeup or personal sensitivity towards the drug itself.

Those who are starting to use modafinil for the first time can experience non-responses, but those with higher doses and/or long term usage will quickly build up a tolerance.

If you are a new user, starting with a dose of 50–100 mg, increase it to 200 mg or higher and test if the effects kick in. In doing so, keep yourself busy. Don’t wait for the active substance to kick in.

Another trick is to combine it with coffee. In fact, caffeine mixes well with smart drugs such as modafinil and can help the nootropic’s effects show faster.

If you are a long-term user, try these tricks: halt taking it for 1 week to 1 month; reduce modafinil intake to 1-3 times/week; and finally, reduce the dosage amount to 200-300mg.

It is important to note that there might be other factors contributing to the low effects of modafinil so pay close attention to your diet, medication, environment and sleep routine, to try and identify the culprit.

Is modafinil safe?

Taking smart drugs in low doses on a daily basis is safe and healthy. You may start to feel irritated after many days of use, but this will only last for short periods before you return back into normal again.

However, if you are on a prescription for either Narcolepsy or other conditions such as ADHD and chronic illnesses like multiple sclerosis it is best to follow the doctor’s advice.

For infrequent users looking to enhance their competitive edge, it’s best to take the smart drug 1–4 times per week or less, mainly consuming it on the days that require you to be performing at a higher level.

Some individuals take it once or twice per month just to help with those really important projects when they’re in the need for a little extra mental ‘boost’.

Frequent users looking for everyday cognitive enhancement and taking modafinil smart drug every morning to enhance their workday performance should know how it is done properly. In order to sustain the daily intake, it’s best to have a good routine with modafinil use. Since the smart drug cannot be fully eliminated from your body, it’s important not to drink alcohol or smoke cigarettes while taking this supplement. Eat healthily and get plenty of sleep each night for best results.


Modafinil as seen in the media​

Don't just take our word for it - have a look at what some of the most reputable news outlets have had to say about the uses and benefits of Modafinil